CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Aspartate-semialdehyde dehydrogenase

Enzyme Information

1.2.1.11
Aspartate-semialdehyde dehydrogenase.
based on mapping to UniProt Q9KQG2
L-aspartate 4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate + NADPH.

UniProtKB Entries (1)

Q9KQG2
DHAS1_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
Aspartate-semialdehyde dehydrogenase 1

PDB Structure

PDB 3PZR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Pavlovsky, A.G., Liu, X., Faehnle, C.R., Potente, N., Viola, R.E.
Chem.Biol.Drug Des.