CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.58.1360
Functional Family Histone lysine demethylase PHF8

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O75151

UniProtKB Entries (1)

O75151
PHF2_HUMAN
Homo sapiens
Lysine-specific demethylase PHF2

PDB Structure

PDB 3PU8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for human PHF2 Jumonji domain interaction with metal ions.
Horton, J.R., Upadhyay, A.K., Hashimoto, H., Zhang, X., Cheng, X.
J.Mol.Biol.