CATH Classification

Domain Context

CATH Clusters

Superfamily DNA polymerase, Y-family, little finger domain
Functional Family DNA polymerase IV

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q97W02
DPO4_SULSO
Sulfolobus solfataricus P2
DNA polymerase IV

PDB Structure

PDB 3PR5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase.
Kirouac, K.N., Suo, Z., Ling, H.
J.Mol.Biol.