CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P13714
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P13714
LDH_BACSU
Bacillus subtilis subsp. subtilis str. 168
L-lactate dehydrogenase

PDB Structure

PDB 3PQD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+
zhang, Y., Garavito, R.M.
To be Published