CATH Classification

Domain Context

CATH Clusters

Superfamily Peptide deformylase
Functional Family Peptide deformylase

Enzyme Information

3.5.1.88
Peptide deformylase.
based on mapping to UniProt Q9FUZ2
Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide.
-!- Requires at least a dipeptide for an efficient rate of reaction. -!- N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. -!- Differs in substrate specificity from EC 3.5.1.27 and EC 3.5.1.31.

UniProtKB Entries (1)

Q9FUZ2
DEF1B_ARATH
Arabidopsis thaliana
Peptide deformylase 1B, chloroplastic/mitochondrial

PDB Structure

PDB 3PN6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis.
Fieulaine, S., Boularot, A., Artaud, I., Desmadril, M., Dardel, F., Meinnel, T., Giglione, C.
Plos Biol.