CATH Domain 3pheA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily	3.30.70.270
Functional Family

Enzyme Information

UniProtKB Entries (1)

D0PY27_9HEPC

Hepacivirus C

RNA-directed RNA polymerase

PDB Structure

PDB	3PHE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Quinolones as HCV NS5B polymerase inhibitors. Kumar, D.V., Rai, R., Brameld, K.A., Somoza, J.R., Rajagopalan, R., Janc, J.W., Xia, Y.M., Ton, T.L., Shaghafi, M.B., Hu, H., Lehoux, I., To, N., Young, W.B., Green, M.J. Bioorg.Med.Chem.Lett.