1 keywords

CATH Domain 3p7mA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.110 L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
Homologous Superfamily 3.90.110.10 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt Q8G942
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

Q8G942
Q8G942_FRATL
Francisella tularensis subsp. tularensis
Malate dehydrogenase

PDB Structure

PDB 3P7M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4
Osinski, T., Cymborowski, M., Zimmerman, M.D., Gordon, E., Grimshaw, S., Skarina, T., Chruszcz, M., Savchenko, A., Anderson, W., Minor, W.
To be Published