CATH Classification

Domain Context

CATH Clusters

Superfamily Transthyretin/hydroxyisourate hydrolase domain
Functional Family Transthyretin

Enzyme Information

UniProtKB Entries (1)

P02766
TTHY_HUMAN
Homo sapiens
Transthyretin

PDB Structure

PDB 3P3S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Alhamadsheh, M.M., Connelly, S., Cho, A., Reixach, N., Powers, E.T., Pan, D.W., Wilson, I.A., Kelly, J.W., Graef, I.A.
Sci Transl Med