CATH Classification

Domain Context

CATH Clusters

Superfamily tRNA intron endonuclease, N-terminal domain
Functional Family

Enzyme Information

4.6.1.16
tRNA-intron lyase.
based on mapping to UniProt Q9YBF1
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.

UniProtKB Entries (1)

Q9YE85
Q9YE85_AERPE
Aeropyrum pernix K1
Uncharacterized protein

PDB Structure

PDB 3P1Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
Hirata, A., Kitajima, T., Hori, H.
Nucleic Acids Res.