CATH Domain 3owoA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1090	Dehydroquinate synthase-like, alpha domain
	1.20.1090.10	Dehydroquinate synthase-like - alpha domain

Domain Context

CATH Clusters

Superfamily	Dehydroquinate synthase-like - alpha domain
Functional Family	Aldehyde-alcohol dehydrogenase

Enzyme Information

1.1.1.1

Alcohol dehydrogenase.

based on mapping to UniProt P0DJA2

(1) A primary alcohol + NAD(+) = an aldehyde + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.

-!- Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. -!- The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.

UniProtKB Entries (1)

P0DJA2

ADH2_ZYMMO

Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821

Alcohol dehydrogenase 2

PDB Structure

PDB	3OWO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of iron-dependent alcohol dehydrogenase 2 from Zymomonas mobilis ZM4 with and without NAD+ cofactor Moon, J.H., Lee, H.J., Park, S.Y., Song, J.M., Park, M.Y., Park, H.M., Sun, J., Park, J.H., Kim, B.Y., Kim, J.S. J.Mol.Biol.