CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family Ribonuclease HII

Enzyme Information

3.1.26.4
Ribonuclease H.
based on mapping to UniProt Q9X017
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.

UniProtKB Entries (1)

Q9X017
RNH2_THEMA
Thermotoga maritima MSB8
Ribonuclease HII

PDB Structure

PDB 3O3G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Rychlik, M.P., Chon, H., Cerritelli, S.M., Klimek, P., Crouch, R.J., Nowotny, M.
Mol.Cell