CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.128.20
Functional Family Prostaglandin-H2 D-isomerase

Enzyme Information

5.3.99.2
Prostaglandin-D synthase.
based on mapping to UniProt P41222
(5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
-!- Brings about the opening of the epidioxy bridge.

UniProtKB Entries (1)

P41222
PTGDS_HUMAN
Homo sapiens
Prostaglandin-H2 D-isomerase

PDB Structure

PDB 3O2Y
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
Zhou, Y., Shaw, N., Li, Y., Zhao, Y., Zhang, R., Liu, Z.-J.
To be Published