CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.248
Salutaridine reductase (NADPH).
based on mapping to UniProt Q071N0
Salutaridinol + NADP(+) = salutaridine + NADPH.
-!- Catalyzes the reversible reduction of salutaridine to salutaridinol, which is a direct precursor of morphinan alkaloids in the poppy plant.

UniProtKB Entries (1)

Q071N0
SALR_PAPSO
Papaver somniferum
Salutaridine reductase

PDB Structure

PDB 3O26
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The atomic structure of salutaridine reductase from the opium poppy Papaver somniferum.
Higashi, Y., Kutchan, T.M., Smith, T.J.
J.Biol.Chem.