CATH Classification

Domain Context

CATH Clusters

Superfamily Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Functional Family

Enzyme Information

6.1.1.4
Leucine--tRNA ligase.
based on mapping to UniProt O66680
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).

UniProtKB Entries (1)

O66680
SYLA_AQUAE
Aquifex aeolicus VF5
Leucine--tRNA ligase subunit alpha

PDB Structure

PDB 3O0A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Wild Type and Two Mutants of the Cp1 Hydrolytic Domain from Aquifex Aeolicus Leucyl-tRNA Synthetase
Cura, V., Olieric, N., Guichard, A., Wang, E.-D., Moras, D., Eriani, G., Cavarelli, J.
To be Published