CATH Classification

Domain Context

CATH Clusters

Superfamily Hedgehog/Intein (Hint) domain
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P74750
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P74750
DPO3A_SYNY3
Synechocystis sp. PCC 6803 substr. Kazusa
DNA polymerase III subunit alpha

PDB Structure

PDB 3NZM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications.
Callahan, B.P., Topilina, N.I., Stanger, M.J., Van Roey, P., Belfort, M.
Nat.Struct.Mol.Biol.