CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.10 | Deoxyribonuclease I; Chain A |
|
3.60.10.10 | Endonuclease/exonuclease/phosphatase |
Domain Context
CATH Clusters
| Superfamily | Endonuclease/exonuclease/phosphatase |
| Functional Family | CCR4-NOT transcription complex subunit 6 like |
Enzyme Information
| 3.1.13.4 |
Poly(A)-specific ribonuclease.
based on mapping to UniProt Q96LI5
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.
|
UniProtKB Entries (1)
| Q96LI5 |
CNO6L_HUMAN
Homo sapiens
CCR4-NOT transcription complex subunit 6-like
|
PDB Structure
| PDB | 3NGO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Embo J.
|