CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.42.10
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P29074
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P29074
PTN4_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 4

PDB Structure

PDB 3NFL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death.
Babault, N., Cordier, F., Lafage, M., Cockburn, J., Haouz, A., Prehaud, C., Rey, F.A., Delepierre, M., Buc, H., Lafon, M., Wolff, N.
Structure