CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1240 | Zincin-like |
|
3.90.1240.10 | Metalloproteases ("zincins"), catalytic domain like |
Domain Context
CATH Clusters
| Superfamily | Metalloproteases ("zincins"), catalytic domain like |
| Functional Family | Botulinum neurotoxin type A |
Enzyme Information
| 3.4.24.69 |
Bontoxilysin.
based on mapping to UniProt Q7B8V4
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (1)
| Q7B8V4 |
Q7B8V4_CLOBO
Clostridium botulinum
BoNT/A
|
PDB Structure
| PDB | 3NF3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A.
Plos One
|