CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 1
Functional Family Aldehyde dehydrogenase, mitochondrial

Enzyme Information

1.2.1.3
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt P05091
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.

UniProtKB Entries (1)

P05091
ALDH2_HUMAN
Homo sapiens
Aldehyde dehydrogenase, mitochondrial

PDB Structure

PDB 3N80
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformational Selection During Catalysis: The role of Threonine 244 in ALDH2
Ho, K.-K., Gonzalez-Segura, L., Perez-Miller, S., Weiner, H., Hurley, T.D.
To be published