CATH Classification

Domain Context

CATH Clusters

Superfamily 1.25.40.10
Functional Family

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt P97443
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

P97443
SMYD1_MOUSE
Mus musculus
Histone-lysine N-methyltransferase Smyd1

PDB Structure

PDB 3N71
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Cardiac-specific Histone Methyltransferase SmyD1 Reveals Unusual Active Site Architecture.
Sirinupong, N., Brunzelle, J., Ye, J., Pirzada, A., Nico, L., Yang, Z.
J.Biol.Chem.