CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Dipeptidyl peptidase 2

Enzyme Information

3.4.14.2
Dipeptidyl-peptidase II.
based on mapping to UniProt Q9UHL4
Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.
-!- A lysosomal serine-type peptidase maximally active at acidic pH. -!- Cleaves Lys-Ala-naphthylamide. -!- Belongs to peptidase family S28.

UniProtKB Entries (1)

Q9UHL4
DPP2_HUMAN
Homo sapiens
Dipeptidyl peptidase 2

PDB Structure

PDB 3N0T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human dipeptidyl peptidase DPP7
Dobrovetsky, E., Khutoreskaya, G., Seitova, A., Crombet, L., Cossar, D., Pagannon, S., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Hassell, A., Shewchuk, L., Haffner, C., Bochkarev, A.
To be Published