CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 3 | Alpha Beta | 
|   | 3.30 | 2-Layer Sandwich | 
|   | 3.30.505 | SHC Adaptor Protein | 
|   | 3.30.505.10 | SH2 domain | 
Domain Context
CATH Clusters
| Superfamily | SH2 domain | 
| Functional Family | Growth factor receptor-bound protein 2 | 
Enzyme Information
UniProtKB Entries (1)
| P05067 | A4_HUMAN Homo sapiens Amyloid-beta precursor protein | 
PDB Structure
| PDB | 3MXC | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | |
| Primary Citation | Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain. J.Mol.Biol. | 
