CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family 6,7-dimethyl-8-ribityllumazine synthase

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt P66038
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

P66038
RISB_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
6,7-dimethyl-8-ribityllumazine synthase

PDB Structure

PDB 3MK3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target.
Kumar, P., Singh, M., Karthikeyan, S.
Acta Crystallogr.,Sect.D