CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family

Enzyme Information

1.1.1.262
4-hydroxythreonine-4-phosphate dehydrogenase.
based on mapping to UniProt P58719
4-phosphooxy-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO(2) + NADH.
-!- The enzyme is part of the biosynthesis pathway of the coenzyme pyridoxal 5'-phosphate found in anaerobic bacteria.

UniProtKB Entries (1)

P58719
PDXA_YERPE
Yersinia pestis
4-hydroxythreonine-4-phosphate dehydrogenase

PDB Structure

PDB 3LXY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of 4-hydroxythreonine-4-phosphate dehydrogenase from Yersinia pestis CO92
Nocek, B., Maltseva, N., Kwon, K., Makowska-Grzyska, M., Anderson, W., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published