CATH Classification

Domain Context

CATH Clusters

Superfamily Enolpyruvate transferase domain
Functional Family UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Enzyme Information

2.5.1.7
UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
based on mapping to UniProt P33038
Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP- N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.

UniProtKB Entries (1)

P33038
MURA_ENTCC
Enterobacter cloacae subsp. cloacae ATCC 13047
UDP-N-acetylglucosamine 1-carboxyvinyltransferase

PDB Structure

PDB 3LTH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
Han, H., Yang, Y., Olesen, S.H., Becker, A., Betzi, S., Schonbrunn, E.
Biochemistry