CATH Domain 3lnnA03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.50	OB fold (Dihydrolipoamide Acetyltransferase, E2P)
	2.40.50.100	RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain

Domain Context

CATH Clusters

Superfamily	2.40.50.100
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q1LCD7_CUPMC

Cupriavidus metallidurans CH34

Membrane fusion protein (MFP-RND) heavy metal cation tricomponent efflux HmxB (CzcB-like)

PDB Structure

PDB	3LNN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems. De Angelis, F., Lee, J.K., O'Connell, J.D., Miercke, L.J., Verschueren, K.H., Srinivasan, V., Bauvois, C., Govaerts, C., Robbins, R.A., Ruysschaert, J.M., Stroud, R.M., Vandenbussche, G. Proc.Natl.Acad.Sci.USA