CATH Classification

Domain Context

CATH Clusters

Superfamily PWWP, helical domain
Functional Family DNA methyltransferase 3 alpha

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt Q9Y6K1
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

Q9Y6K1
DNM3A_HUMAN
Homo sapiens
DNA (cytosine-5)-methyltransferase 3A

PDB Structure

PDB 3LLR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and histone binding ability characterizations of human PWWP domains.
Wu, H., Zeng, H., Lam, R., Tempel, W., Amaya, M.F., Xu, C., Dombrovski, L., Qiu, W., Wang, Y., Min, J.
Plos One