CATH Classification

Domain Context

CATH Clusters

Superfamily 3.60.21.10
Functional Family Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt Q08209
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P63098
CANB1_HUMAN
Homo sapiens
Calcineurin subunit B type 1

PDB Structure

PDB 3LL8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling.
Li, H., Pink, M.D., Murphy, J.G., Stein, A., Dell'acqua, M.L., Hogan, P.G.
Nat.Struct.Mol.Biol.