CATH Classification

Domain Context

CATH Clusters

Superfamily LON domain-like
Functional Family Lon protease

Enzyme Information

3.4.21.53
Endopeptidase La.
based on mapping to UniProt P0A9M0
Hydrolysis of proteins in presence of ATP.
-!- ATP hydrolysis is linked with peptide bond hydrolysis. -!- Vanadate inhibits both reactions. -!- A similar enzyme occurs in animal mitochondria. -!- Belongs to peptidase family S16.

UniProtKB Entries (1)

P0A9M0
LON_ECOLI
Escherichia coli K-12
Lon protease

PDB Structure

PDB 3LJC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the N-terminal fragment of Escherichia coli Lon protease
Li, M., Gustchina, A., Rasulova, F.S., Melnikov, E.E., Maurizi, M.R., Rotanova, T.V., Dauter, Z., Wlodawer, A.
Acta Crystallogr.,Sect.D