CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt Q6GIL8
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.

UniProtKB Entries (1)

Q6GIL8
G3P1_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Glyceraldehyde-3-phosphate dehydrogenase 1

PDB Structure

PDB 3LC7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism.
Mukherjee, S., Dutta, D., Saha, B., Das, A.K.
J.Mol.Biol.