CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.850 | Kinesin |
|
3.40.850.10 | Kinesin motor domain |
Domain Context
CATH Clusters
| Superfamily | Kinesin motor domain |
| Functional Family | Kinesin-like protein KIF11 |
Enzyme Information
UniProtKB Entries (1)
| P52732 |
KIF11_HUMAN
Homo sapiens
Kinesin-like protein KIF11
|
PDB Structure
| PDB | 3L9H |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5.
Bioorg.Med.Chem.Lett.
|