CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome b-c1 complex subunit 8
Functional Family Cytochrome b-c1 complex subunit 8

Enzyme Information
Quinol--cytochrome-c reductase.
based on mapping to UniProt D0VX32
Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H(+).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and C(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC

UniProtKB Entries (1)

Gallus gallus
Cytochrome b-c1 complex subunit Rieske, mitochondrial

PDB Structure

PDB 3L71
External Links
Primary Citation
Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the Qo site of the BC1 compl and fix the rieske iron-sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "DISTAL" Qo inhibitors.
Huang, L., Berry, E.A.
To be Published