CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.900 | Dbl Homology Domain; Chain A |
|
1.20.900.10 | Dbl homology (DH) domain |
Domain Context
CATH Clusters
| Superfamily | Dbl homology (DH) domain |
| Functional Family | Rho guanine nucleotide exchange factor (GEF) 11 |
Enzyme Information
UniProtKB Entries (1)
| O15085 |
ARHGB_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 11
|
PDB Structure
| PDB | 3KZ1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem.
|