CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
1.20.5.300 |
Domain Context
CATH Clusters
| Superfamily | 1.20.5.300 |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| P03420 |
FUS_HRSVA
Human respiratory syncytial virus A2
Fusion glycoprotein F0
|
PDB Structure
| PDB | 3KPE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein.
Proc.Natl.Acad.Sci.USA
|