CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.30 | Glutaredoxin |
|
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
| Superfamily | Glutaredoxin |
| Functional Family | Glutathione peroxidase |
Enzyme Information
| 1.11.1.9 |
Glutathione peroxidase.
based on mapping to UniProt Q8TED1
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
|
UniProtKB Entries (1)
| Q8TED1 |
GPX8_HUMAN
Homo sapiens
Probable glutathione peroxidase 8
|
PDB Structure
| PDB | 3KIJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Two Endoplasmic Reticulum PDI Peroxidases Increase the Efficiency of the Use of Peroxide during Disulfide Bond Formation.
J.Mol.Biol.
|