CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1170.60
Functional Family DNA polymerase IV

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q97W02
DPO4_SACS2
Saccharolobus solfataricus P2
DNA polymerase IV

PDB Structure

PDB 3KHH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4.
Rechkoblit, O., Kolbanovskiy, A., Malinina, L., Geacintov, N.E., Broyde, S., Patel, D.J.
Nat.Struct.Mol.Biol.