1 keywords

CATH Domain 3kfjA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.505 SHC Adaptor Protein
Homologous Superfamily 3.30.505.10 SH2 domain

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Growth factor receptor-bound protein 2

Enzyme Information

UniProtKB Entries (1)

P62993
GRB2_HUMAN
Homo sapiens
Growth factor receptor-bound protein 2

PDB Structure

PDB 3KFJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization.
DeLorbe, J.E., Clements, J.H., Teresk, M.G., Benfield, A.P., Plake, H.R., Millspaugh, L.E., Martin, S.F.
J.Am.Chem.Soc.