CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Quinate/shikimate dehydrogenase

Enzyme Information

1.1.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9X5C9
1.1.1.24
Quinate dehydrogenase.
based on mapping to UniProt Q9X5C9
Quinate + NAD(+) = 3-dehydroquinate + NADH.
-!- The enzyme is specific for quinate as substrate; phenylpyruvate, phenylalanine, cinnamate and shikimate will not act as substrates. -!- NAD(+) cannot be replaced by NADP(+).

UniProtKB Entries (1)

Q9X5C9
AROE_CORGL
Corynebacterium glutamicum ATCC 13032
Quinate/shikimate dehydrogenase (NAD(+))

PDB Structure

PDB 3JYQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination.
Hoppner, A., Schomburg, D., Niefind, K.
Biol.Chem.