CATH Domain 3jxjA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.20	Ankyrin repeat-containing domain

Domain Context

CATH Clusters

Superfamily	Ankyrin repeat-containing domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

TRPV4_CHICK

Gallus gallus

Transient receptor potential cation channel subfamily V member 4

PDB Structure

PDB	3JXJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C. Landoure, G., Zdebik, A.A., Martinez, T.L., Burnett, B.G., Stanescu, H.C., Inada, H., Shi, Y., Taye, A.A., Kong, L., Munns, C.H., Choo, S.S., Phelps, C.B., Paudel, R., Houlden, H., Ludlow, C.L., Caterina, M.J., Gaudet, R., Kleta, R., Fischbeck, K.H., Sumner, C.J. Nat.Genet.