CATH Classification

Domain Context

CATH Clusters

Superfamily Hexapeptide repeat proteins
Functional Family K1 capsule O-acetyltransferase

Enzyme Information

2.3.1.136
Polysialic-acid O-acetyltransferase.
based on mapping to UniProt A1ADJ6
Acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.
-!- Acts only on substrates containing more than 14 sialosyl residues. -!- Catalyzes the modification of capsular polysaccharides in some strains of Escherichia coli.

UniProtKB Entries (1)

A1ADJ6
NEUO_ECOK1
Escherichia coli APEC O1
Polysialic acid O-acetyltransferase

PDB Structure

PDB 3JQY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure analysis of the polysialic acid specific O-acetyltransferase NeuO
Schulz, E.C., Bergfeld, A.K., Ficner, R., Muhlenhoff, M.
PLoS ONE