CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Pteridine reductase

Enzyme Information

UniProtKB Entries (1)

Q581W1
Q581W1_TRYB2
Trypanosoma brucei brucei TREU927
Pteridine reductase, putative

PDB Structure

PDB 3JQF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
Tulloch, L.B., Martini, V.P., Iulek, J., Huggan, J.K., Lee, J.H., Gibson, C.L., Smith, T.K., Suckling, C.J., Hunter, W.N.
J.Med.Chem.