CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.150.810
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UBT6
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9UBT6
POLK_HUMAN
Homo sapiens
DNA polymerase kappa

PDB Structure

PDB 3IN5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion
Vasquez-Del Carpio, R., Silverstein, T.D., Lone, S., Swan, M.K., Choudhury, J.R., Johnson, R.E., Prakash, S., Prakash, L., Aggarwal, A.K.
PLOS ONE