CATH Classification

Domain Context

CATH Clusters

Superfamily Transthyretin/hydroxyisourate hydrolase domain
Functional Family Transthyretin

Enzyme Information

UniProtKB Entries (1)

P02766
TTHY_HUMAN
Homo sapiens
Transthyretin

PDB Structure

PDB 3IMW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
Choi, S., Reixach, N., Connelly, S., Johnson, S.M., Wilson, I.A., Kelly, J.W.
J.Am.Chem.Soc.