CATH Classification

Domain Context

CATH Clusters

Superfamily Sec63 N-terminal domain-like domain
Functional Family Pre-mRNA-splicing helicase BRR2

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P32639
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P32639
BRR2_YEAST
Saccharomyces cerevisiae S288C
Pre-mRNA-splicing helicase BRR2

PDB Structure

PDB 3IM1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase
Pena, V., Jovin, S.M., Fabrizio, P., Orlowski, J., Bujnicki, J.M., Hrmann, R.L., Wahl, M.C.
To be Published