CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family cAMP-dependent protein kinase type I regulatory subunit

Enzyme Information

UniProtKB Entries (1)

P00514
KAP0_BOVIN
Bos taurus
CAMP-dependent protein kinase type I-alpha regulatory subunit

PDB Structure

PDB 3IIA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design.
Badireddy, S., Yunfeng, G., Ritchie, M., Akamine, P., Wu, J., Kim, C.W., Taylor, S.S., Qingsong, L., Swaminathan, K., Anand, G.S.
Mol.Cell Proteomics