CATH Classification

Domain Context

CATH Clusters

Superfamily Galactose-binding domain-like
Functional Family

Enzyme Information

3.1.1.84
Cocaine esterase.
based on mapping to UniProt Q9L9D7
Cocaine + H(2)O = ecgonine methyl ester + benzoate.
-!- Rhodococcus sp. strain MB1 and Pseudomonas maltophilia strain MB11L can utilize cocaine as sole source of carbon and energy.

UniProtKB Entries (1)

Q9L9D7
COCE_RHOSM
Rhodococcus sp. MB1 'Bresler 1999'
Cocaine esterase

PDB Structure

PDB 3IDA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
Brim, R.L., Nance, M.R., Youngstrom, D.W., Narasimhan, D., Zhan, C.G., Tesmer, J.J., Sunahara, R.K., Woods, J.H.
Mol.Pharmacol.