CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Collagenase 3 |
Enzyme Information
| 3.4.24.- |
Metalloendopeptidases.
based on mapping to UniProt P45452
|
UniProtKB Entries (1)
| P45452 |
MMP13_HUMAN
Homo sapiens
Collagenase 3
|
PDB Structure
| PDB | 3I7I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors.
Bioorg.Med.Chem.Lett.
|