CATH Domain 3i3rA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family

Enzyme Information

UniProtKB Entries (1)

A7ASX7_BABBO

Babesia bovis

Bifunctional dihydrofolate reductase-thymidylate synthase

PDB Structure

PDB	3I3R
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Begley, D.W., Edwards, T.E., Raymond, A.C., Smith, E.R., Hartley, R.C., Abendroth, J., Sankaran, B., Lorimer, D.D., Myler, P.J., Staker, B.L., Stewart, L.J. Acta Crystallogr.,Sect.F