CATH Classification

Domain Context

CATH Clusters

Superfamily 3.50.50.100
Functional Family Sulfide-quinone reductase

Enzyme Information

1.8.5.4
Bacterial sulfide:quinone reductase.
based on mapping to UniProt O67931
n sulfide + n quinone = polysulfide + n quinol.
-!- Ubiquinone, plastoquinone or menaquinone can act as acceptor in different species. -!- This enzyme catalyzes the formation of sulfur globules. -!- It repeats the catalytic cycle without releasing the product, producing a polysulfide of up to 10 sulfur atoms. -!- The reaction stops when the maximum length of the polysulfide that can be accommodated in the sulfide oxidation pocket is achieved. -!- The enzyme also plays an important role in anoxygenic bacterial photosynthesis. -!- Cf. EC 1.8.5.8.

UniProtKB Entries (1)

O67931
SQRD_AQUAE
Aquifex aeolicus VF5
Sulfide-quinone reductase

PDB Structure

PDB 3HYX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration
Marcia, M., Ermler, U., Peng, G.H., Michel, H.
Proc.Natl.Acad.Sci.USA