CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family 3-phosphoinositide-dependent protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15530
PDPK1_HUMAN
Homo sapiens
3-phosphoinositide-dependent protein kinase 1

PDB Structure

PDB 3HRF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1.
Hindie, V., Stroba, A., Zhang, H., Lopez-Garcia, L.A., Idrissova, L., Zeuzem, S., Hirschberg, D., Schaeffer, F., Jrgensen, T.J., Engel, M., Alzari, P.M., Biondi, R.M.
Nat.Chem.Biol.